Interações medicamentosas
Amphotericin b liposomal + Benazepril
Gravidade: Moderada
Amphotericin b liposomal and Benazepril: moderate interaction.
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Resumo
Amphotericin B can cause infusion-related hypotension and renal toxicity, which may be amplified by an ACE inhibitor. Volume depletion and reduced renal function increase the likelihood of problems.
O que esta interação significa em palavras simples
Amphotericin b liposomal and Benazepril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Benazepril belongs to Cardiovascular.
Por que acontece
Additive hypotensive effect, with amphotericin nephrotoxicity and ACE inhibitor loss of efferent arteriolar tone compounding renal risk.
O que fazer
Monitor blood pressure, serum creatinine and potassium during amphotericin therapy and temporarily hold benazepril if hypotension or renal decline develops.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Benazepril
- Aliskiren + Benazepril Contraindicada
- Benazepril + Sacubitril / valsartan Contraindicada
- Benazepril + Sacubitril-valsartan Contraindicada
- Amifostine + Benazepril Grave
- Amiloride + Benazepril Grave
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Grave
Outras interações de Amphotericin b liposomal
- Amlodipine-benazepril + Amphotericin b liposomal Moderada
- Amphotericin b liposomal + Captopril-hydrochlorothiazide Moderada
- Amphotericin b liposomal + Deflazacort Moderada
- Amphotericin b liposomal + Dichlorphenamide Moderada
- Amphotericin b liposomal + Ifosfamide Moderada
- Amphotericin b liposomal + Lomustine Moderada
Perguntas frequentes
Can I take Amphotericin b liposomal with Benazepril?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Benazepril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause infusion-related hypotension and renal toxicity, which may be amplified by an ACE inhibitor. Volume depletion and reduced renal function increase the likelihood of problems.
How serious is the interaction between Amphotericin b liposomal and Benazepril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum creatinine and potassium during amphotericin therapy and temporarily hold benazepril if hypotension or renal decline develops.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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