Interações medicamentosas
Amphotericin b liposomal + Lomustine
Gravidade: Moderada
Amphotericin b liposomal and Lomustine: moderate interaction.
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Resumo
Amphotericin B can cause kidney injury and infusion reactions, while lomustine causes myelosuppression and may add to toxicity. The extent of any true interaction is poorly defined.
O que esta interação significa em palavras simples
Amphotericin b liposomal and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Lomustine belongs to Oncology.
Por que acontece
Mechanism not established; possible additive renal and hematologic toxicity.
O que fazer
Monitor renal function, electrolytes and blood counts, and observe for hypotension or bronchospasm during infusions.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Lomustine
- Adenovirus types 4 and 7 live + Lomustine Contraindicada
- Bcg vaccine live + Lomustine Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Lomustine Contraindicada
- Lomustine + Measles mumps and rubella vaccine Contraindicada
- Lomustine + Measles mumps and rubella vaccine live Contraindicada
- Lomustine + Measles mumps rubella and varicella vaccine live Contraindicada
Outras interações de Amphotericin b liposomal
- Amlodipine-benazepril + Amphotericin b liposomal Moderada
- Amphotericin b liposomal + Benazepril Moderada
- Amphotericin b liposomal + Captopril-hydrochlorothiazide Moderada
- Amphotericin b liposomal + Deflazacort Moderada
- Amphotericin b liposomal + Dichlorphenamide Moderada
- Amphotericin b liposomal + Ifosfamide Moderada
Perguntas frequentes
Can I take Amphotericin b liposomal with Lomustine?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause kidney injury and infusion reactions, while lomustine causes myelosuppression and may add to toxicity. The extent of any true interaction is poorly defined.
How serious is the interaction between Amphotericin b liposomal and Lomustine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, electrolytes and blood counts, and observe for hypotension or bronchospasm during infusions.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
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