Interações medicamentosas
Amphotericin b liposomal + Ifosfamide
Gravidade: Moderada
Amphotericin b liposomal and Ifosfamide: moderate interaction.
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Resumo
Both drugs can injure the kidney, so combined use may increase the risk of renal impairment. Infusion-related reactions such as bronchospasm and hypotension are also described with amphotericin.
O que esta interação significa em palavras simples
Amphotericin b liposomal and Ifosfamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Ifosfamide belongs to Oncology.
Por que acontece
Additive nephrotoxicity; the mechanism for any other enhanced toxicity is not established.
O que fazer
Monitor serum creatinine, electrolytes (potassium, magnesium) and urine output regularly, and maintain adequate hydration. Consider an alternative antifungal if renal function declines.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contraindicada
- Ifosfamide + Measles mumps and rubella vaccine Contraindicada
- Ifosfamide + Measles mumps and rubella vaccine live Contraindicada
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contraindicada
- Ifosfamide + Measles vaccine Contraindicada
- Ifosfamide + Rotavirus oral vaccine live Contraindicada
Outras interações de Amphotericin b liposomal
- Amlodipine-benazepril + Amphotericin b liposomal Moderada
- Amphotericin b liposomal + Benazepril Moderada
- Amphotericin b liposomal + Captopril-hydrochlorothiazide Moderada
- Amphotericin b liposomal + Deflazacort Moderada
- Amphotericin b liposomal + Dichlorphenamide Moderada
- Amphotericin b liposomal + Lomustine Moderada
Perguntas frequentes
Can I take Amphotericin b liposomal with Ifosfamide?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Ifosfamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can injure the kidney, so combined use may increase the risk of renal impairment. Infusion-related reactions such as bronchospasm and hypotension are also described with amphotericin.
How serious is the interaction between Amphotericin b liposomal and Ifosfamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine, electrolytes (potassium, magnesium) and urine output regularly, and maintain adequate hydration. Consider an alternative antifungal if renal function declines.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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