Interações medicamentosas
Amlodipine-olmesartan-hydrochlorothiazide + Colestipol
Gravidade: Moderada
Amlodipine-olmesartan-hydrochlorothiazide and Colestipol: moderate interaction.
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Resumo
Colestipol binds hydrochlorothiazide in the gut and reduces its oral absorption, which may weaken the diuretic and antihypertensive effect. Olmesartan absorption may also be reduced by bile acid sequestrants.
O que esta interação significa em palavras simples
Amlodipine-olmesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Colestipol belongs to Cardiovascular.
Por que acontece
Bile acid sequestrant resin binds drugs in the gastrointestinal tract, decreasing absorption.
O que fazer
Give the combination product at least 4 hours before colestipol, or 4 to 6 hours after it. Monitor blood pressure.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicada
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicada
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicada
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Grave
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Grave
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Grave
Outras interações de Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderada
- Atenolol-chlorthalidone + Colestipol Moderada
- Azilsartan-chlorthalidone + Colestipol Moderada
- Candesartan-hydrochlorothiazide + Colestipol Moderada
- Captopril-hydrochlorothiazide + Colestipol Moderada
- Chenodeoxycholic acid + Colestipol Moderada
Perguntas frequentes
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Colestipol?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol binds hydrochlorothiazide in the gut and reduces its oral absorption, which may weaken the diuretic and antihypertensive effect. Olmesartan absorption may also be reduced by bile acid sequestrants.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the combination product at least 4 hours before colestipol, or 4 to 6 hours after it. Monitor blood pressure.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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