Interações medicamentosas
Candesartan-hydrochlorothiazide + Colestipol
Gravidade: Moderada
Candesartan-hydrochlorothiazide and Colestipol: moderate interaction.
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Resumo
Colestipol binds hydrochlorothiazide in the gut and reduces its absorption, which can blunt the diuretic and antihypertensive effect. The effect is dose-timing dependent and can be avoided by separating administration.
O que esta interação significa em palavras simples
Candesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Candesartan-hydrochlorothiazide belongs to Cardiovascular; Colestipol belongs to Cardiovascular.
Por que acontece
Bile acid sequestrant binds hydrochlorothiazide in the gastrointestinal tract, reducing absorption.
O que fazer
Give hydrochlorothiazide at least 4 hours before or after colestipol, and monitor blood pressure.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Candesartan-hydrochlorothiazide
- Aliskiren + Candesartan-hydrochlorothiazide Contraindicada
- Candesartan-hydrochlorothiazide + Dofetilide Contraindicada
- Candesartan-hydrochlorothiazide + Sparsentan Contraindicada
- Acemetacin + Candesartan-hydrochlorothiazide Grave
- Amifostine + Candesartan-hydrochlorothiazide Grave
- Amiloride + Candesartan-hydrochlorothiazide Grave
Outras interações de Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderada
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderada
- Atenolol-chlorthalidone + Colestipol Moderada
- Azilsartan-chlorthalidone + Colestipol Moderada
- Captopril-hydrochlorothiazide + Colestipol Moderada
- Chenodeoxycholic acid + Colestipol Moderada
Perguntas frequentes
Can I take Candesartan-hydrochlorothiazide with Colestipol?
MediHelp rates the interaction as moderate. Candesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol binds hydrochlorothiazide in the gut and reduces its absorption, which can blunt the diuretic and antihypertensive effect. The effect is dose-timing dependent and can be avoided by separating administration.
How serious is the interaction between Candesartan-hydrochlorothiazide and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give hydrochlorothiazide at least 4 hours before or after colestipol, and monitor blood pressure.
What other medicines interact with Candesartan-hydrochlorothiazide?
MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.
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