Interações medicamentosas
Amlodipine-hydrochlorothiazide-valsartan + Colestipol
Gravidade: Moderada
Amlodipine-hydrochlorothiazide-valsartan and Colestipol: moderate interaction.
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Resumo
Colestipol is a bile acid sequestrant that binds hydrochlorothiazide in the gut and reduces its absorption. This can lower the diuretic and antihypertensive effect of the thiazide.
O que esta interação significa em palavras simples
Amlodipine-hydrochlorothiazide-valsartan and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Colestipol belongs to Cardiovascular.
Por que acontece
Binding of hydrochlorothiazide by the resin in the gastrointestinal tract, reducing absorption.
O que fazer
Give the hydrochlorothiazide-containing product at least 2 hours before or 4 to 6 hours after colestipol, and monitor blood pressure.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicada
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Contraindicada
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Contraindicada
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Grave
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Grave
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Grave
Outras interações de Colestipol
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderada
- Atenolol-chlorthalidone + Colestipol Moderada
- Azilsartan-chlorthalidone + Colestipol Moderada
- Candesartan-hydrochlorothiazide + Colestipol Moderada
- Captopril-hydrochlorothiazide + Colestipol Moderada
- Chenodeoxycholic acid + Colestipol Moderada
Perguntas frequentes
Can I take Amlodipine-hydrochlorothiazide-valsartan with Colestipol?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that binds hydrochlorothiazide in the gut and reduces its absorption. This can lower the diuretic and antihypertensive effect of the thiazide.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the hydrochlorothiazide-containing product at least 2 hours before or 4 to 6 hours after colestipol, and monitor blood pressure.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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