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Interações medicamentosas

Amoxicillin-clavulanic acid + Bcg vaccine live

Gravidade: Moderada

Amoxicillin-clavulanic acid and Bcg vaccine live: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Amoxicillin has limited activity against BCG, but labeling for live bacterial vaccines advises avoiding concurrent antibiotics.

O que esta interação significa em palavras simples

Amoxicillin-clavulanic acid and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Low

Por que acontece

Antibacterial activity may reduce replication of the live vaccine organism, lessening the immune response.

O que fazer

Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Amoxicillin-clavulanic acid with Bcg vaccine live?

MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Amoxicillin has limited activity against BCG, but labeling for live bacterial vaccines advises avoiding concurrent antibiotics.

How serious is the interaction between Amoxicillin-clavulanic acid and Bcg vaccine live?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.

What other medicines interact with Amoxicillin-clavulanic acid?

MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.

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