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Interações medicamentosas

Amoxicillin-clavulanic acid + Eravacycline

Gravidade: Moderada

Amoxicillin-clavulanic acid and Eravacycline: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Eravacycline is a bacteriostatic tetracycline-class antibiotic that could theoretically antagonize beta-lactam killing. Clinical data on this combination are scarce. It matters mainly in severe infections where bactericidal activity is needed.

O que esta interação significa em palavras simples

Amoxicillin-clavulanic acid and Eravacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amoxicillin-clavulanic acid belongs to Anti Bacterial; Eravacycline belongs to Anti Bacterial.

Nível de evidência: Low

Por que acontece

Pharmacodynamic antagonism: growth suppression by a protein synthesis inhibitor reduces beta-lactam bactericidal activity.

O que fazer

Avoid unnecessary combination and use the narrowest effective regimen. If both are needed, monitor clinical and microbiological response.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

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Perguntas frequentes

Can I take Amoxicillin-clavulanic acid with Eravacycline?

MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Eravacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eravacycline is a bacteriostatic tetracycline-class antibiotic that could theoretically antagonize beta-lactam killing. Clinical data on this combination are scarce. It matters mainly in severe infections where bactericidal activity is needed.

How serious is the interaction between Amoxicillin-clavulanic acid and Eravacycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary combination and use the narrowest effective regimen. If both are needed, monitor clinical and microbiological response.

What other medicines interact with Amoxicillin-clavulanic acid?

MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.

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