Interações medicamentosas
Amoxicillin-clavulanic acid + Nivolumab
Gravidade: Leve
Amoxicillin-clavulanic acid and Nivolumab: minor interaction.
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Resumo
Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
O que esta interação significa em palavras simples
Amoxicillin-clavulanic acid and Nivolumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Nivolumab belongs to Oncology.
Por que acontece
Proposed disruption of gut microbiota that may modulate antitumor immune response; not firmly established.
O que fazer
Prescribe the antibiotic only when there is a clear infection indication and keep the course as short as clinically appropriate. Do not withhold needed antibiotics.
O que perguntar ao farmacêutico
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Outras interações de Amoxicillin-clavulanic acid
- Amoxicillin-clavulanic acid + Methotrexate Grave
- Amoxicillin-clavulanic acid + Pexidartinib Grave
- Amoxicillin-clavulanic acid + Pretomanid Grave
- Allopurinol + Amoxicillin-clavulanic acid Moderada
- Amoxicillin-clavulanic acid + Bcg vaccine live Moderada
- Amoxicillin-clavulanic acid + Chloramphenicol Moderada
Outras interações de Nivolumab
- Nivolumab + Thalidomide Grave
- Dexamethasone-tobramycin + Nivolumab Moderada
- Dexamethasone + Nivolumab Moderada
- Efgartigimod / hyaluronidase sc + Nivolumab Moderada
- Efgartigimod alfa + Nivolumab Moderada
- Nivolumab + Ponesimod Moderada
Perguntas frequentes
Can I take Amoxicillin-clavulanic acid with Nivolumab?
MediHelp rates the interaction as minor. Amoxicillin-clavulanic acid and Nivolumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
How serious is the interaction between Amoxicillin-clavulanic acid and Nivolumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prescribe the antibiotic only when there is a clear infection indication and keep the course as short as clinically appropriate. Do not withhold needed antibiotics.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
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