Interações medicamentosas
Atropine iv / + Umeclidinium
Gravidade: Moderada
Atropine iv / and Umeclidinium: moderate interaction.
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Resumo
Systemic atropine adds antimuscarinic effects to inhaled umeclidinium. Tachycardia, dry mouth, urinary retention and constipation may be increased, though single clinical doses of atropine are usually tolerated.
O que esta interação significa em palavras simples
Atropine iv / and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive muscarinic receptor antagonism.
O que fazer
Monitor heart rate and for urinary retention when atropine is given, especially with repeated doses. Avoid long-term combination of systemic antimuscarinics with umeclidinium where possible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Umeclidinium
- Tiotropium + Umeclidinium Grave
- Aclidinium + Umeclidinium Moderada
- Atropine + Umeclidinium Moderada
- Belladonna alkaloids + Umeclidinium Moderada
- Bethanechol + Umeclidinium Moderada
- Dicyclomine + Umeclidinium Moderada
Perguntas frequentes
Can I take Atropine iv / with Umeclidinium?
MediHelp rates the interaction as moderate. Atropine iv / and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic atropine adds antimuscarinic effects to inhaled umeclidinium. Tachycardia, dry mouth, urinary retention and constipation may be increased, though single clinical doses of atropine are usually tolerated.
How serious is the interaction between Atropine iv / and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and for urinary retention when atropine is given, especially with repeated doses. Avoid long-term combination of systemic antimuscarinics with umeclidinium where possible.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine. The full list is on the Umeclidinium page.
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