Interações medicamentosas
Dicyclomine + Umeclidinium
Gravidade: Moderada
Dicyclomine and Umeclidinium: moderate interaction.
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Resumo
Dicyclomine is an antimuscarinic antispasmodic, so combining it with umeclidinium may increase anticholinergic adverse effects including dry mouth, constipation, urinary retention, blurred vision and tachycardia. Systemic umeclidinium exposure is low, but additive effects are possible in vulnerable patients.
O que esta interação significa em palavras simples
Dicyclomine and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicyclomine belongs to Respiratory; Umeclidinium belongs to Respiratory.
Por que acontece
Additive antimuscarinic pharmacodynamic effects.
O que fazer
Avoid unnecessary duplication of anticholinergic therapy, and monitor for urinary retention, constipation and eye symptoms, particularly in older patients.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Umeclidinium
- Tiotropium + Umeclidinium Grave
- Aclidinium + Umeclidinium Moderada
- Atropine iv / + Umeclidinium Moderada
- Atropine + Umeclidinium Moderada
- Belladonna alkaloids + Umeclidinium Moderada
- Bethanechol + Umeclidinium Moderada
Outras interações de Dicyclomine
- Clozapine + Dicyclomine Grave
- Dicyclomine + Henbane Grave
- Dicyclomine + Imipramine Grave
- Dicyclomine + Pramlintide Grave
- Abobotulinumtoxina + Dicyclomine Moderada
- Aclidinium + Dicyclomine Moderada
Perguntas frequentes
Can I take Dicyclomine with Umeclidinium?
MediHelp rates the interaction as moderate. Dicyclomine and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicyclomine is an antimuscarinic antispasmodic, so combining it with umeclidinium may increase anticholinergic adverse effects including dry mouth, constipation, urinary retention, blurred vision and tachycardia. Systemic umeclidinium exposure is low, but additive effects are possible in vulnerable patients.
How serious is the interaction between Dicyclomine and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary duplication of anticholinergic therapy, and monitor for urinary retention, constipation and eye symptoms, particularly in older patients.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
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