Interações medicamentosas
Bethanechol + Umeclidinium
Gravidade: Moderada
Bethanechol and Umeclidinium: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Bethanechol is a muscarinic agonist and umeclidinium is a muscarinic antagonist, so each can oppose the effect of the other. The practical result is reduced efficacy of bethanechol, for example in urinary retention, and the size of the effect with inhaled umeclidinium is uncertain.
O que esta interação significa em palavras simples
Bethanechol and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bethanechol belongs to Gastrointestinal Tract; Umeclidinium belongs to Respiratory.
Por que acontece
Pharmacodynamic antagonism at muscarinic receptors.
O que fazer
Monitor for loss of bethanechol effect, such as persistent urinary retention, and for worsening of airway symptoms; adjust therapy if the response is inadequate.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Umeclidinium
- Tiotropium + Umeclidinium Grave
- Aclidinium + Umeclidinium Moderada
- Atropine iv / + Umeclidinium Moderada
- Atropine + Umeclidinium Moderada
- Belladonna alkaloids + Umeclidinium Moderada
- Dicyclomine + Umeclidinium Moderada
Outras interações de Bethanechol
- Bethanechol + Darifenacin Grave
- Bethanechol + Fesoterodine Grave
- Bethanechol + Oxybutynin Grave
- Bethanechol + Physostigmine Grave
- Amifampridine + Bethanechol Moderada
- Amitriptyline + Bethanechol Moderada
Perguntas frequentes
Can I take Bethanechol with Umeclidinium?
MediHelp rates the interaction as moderate. Bethanechol and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bethanechol is a muscarinic agonist and umeclidinium is a muscarinic antagonist, so each can oppose the effect of the other. The practical result is reduced efficacy of bethanechol, for example in urinary retention, and the size of the effect with inhaled umeclidinium is uncertain.
How serious is the interaction between Bethanechol and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for loss of bethanechol effect, such as persistent urinary retention, and for worsening of airway symptoms; adjust therapy if the response is inadequate.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
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