Interações medicamentosas
Azithromycin + Macimorelin
Gravidade: Grave
Azithromycin and Macimorelin: major interaction.
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Resumo
Macimorelin causes a small QT prolongation and azithromycin can add to it. Combining them increases the risk of torsades de pointes around the diagnostic test.
O que esta interação significa em palavras simples
Azithromycin and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Azithromycin belongs to Anti Bacterial; Macimorelin belongs to Endocrine.
Por que acontece
Additive pharmacodynamic QT prolongation.
O que fazer
Postpone the macimorelin test until azithromycin has been stopped and cleared; azithromycin has a long half-life, so allow a generous washout. Avoid giving both within the testing period.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Azithromycin
- Azithromycin + Cisapride Contraindicada
- Azithromycin + Domperidone Contraindicada
- Azithromycin + Dronedarone Contraindicada
- Azithromycin + Pimozide Contraindicada
- Azithromycin + Piperaquine Contraindicada
- Azithromycin + Thioridazine Contraindicada
Outras interações de Macimorelin
Perguntas frequentes
Can I take Azithromycin with Macimorelin?
MediHelp rates the interaction as major. Azithromycin and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin causes a small QT prolongation and azithromycin can add to it. Combining them increases the risk of torsades de pointes around the diagnostic test.
How serious is the interaction between Azithromycin and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Postpone the macimorelin test until azithromycin has been stopped and cleared; azithromycin has a long half-life, so allow a generous washout. Avoid giving both within the testing period.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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