Interações medicamentosas
Azithromycin + Pasireotide
Gravidade: Grave
Azithromycin and Pasireotide: major interaction.
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Resumo
Both drugs can prolong the QT interval, and pasireotide also causes bradycardia, increasing the risk of torsades de pointes.
O que esta interação significa em palavras simples
Azithromycin and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Azithromycin belongs to Anti Bacterial; Pasireotide belongs to Endocrine.
Por que acontece
Additive QT prolongation, with pasireotide-related bradycardia as a contributing factor.
O que fazer
Monitor ECG and correct potassium and magnesium before and during therapy. Consider an alternative to azithromycin when feasible.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Azithromycin
- Azithromycin + Cisapride Contraindicada
- Azithromycin + Domperidone Contraindicada
- Azithromycin + Dronedarone Contraindicada
- Azithromycin + Pimozide Contraindicada
- Azithromycin + Piperaquine Contraindicada
- Azithromycin + Thioridazine Contraindicada
Outras interações de Pasireotide
- Dronedarone + Pasireotide Contraindicada
- Pasireotide + Pimozide Contraindicada
- Amiodarone + Pasireotide Grave
- Amisulpride + Pasireotide Grave
- Amitriptyline + Pasireotide Grave
- Anagrelide + Pasireotide Grave
Perguntas frequentes
Can I take Azithromycin with Pasireotide?
MediHelp rates the interaction as major. Azithromycin and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can prolong the QT interval, and pasireotide also causes bradycardia, increasing the risk of torsades de pointes.
How serious is the interaction between Azithromycin and Pasireotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium and magnesium before and during therapy. Consider an alternative to azithromycin when feasible.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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