Interações medicamentosas
Aztreonam + Microbiota
Gravidade: Moderada
Aztreonam and Microbiota: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Oral microbiota products contain live bacterial spores intended to recolonize the gut. Systemic antibiotics may reduce spore viability and blunt the preventive effect against recurrent Clostridioides difficile infection, although aztreonam has a narrow Gram-negative spectrum so the effect is likely smaller.
O que esta interação significa em palavras simples
Aztreonam and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity may reduce the viability of the live bacterial spores in the product.
O que fazer
Finish the antibiotic course before starting oral microbiota therapy, and keep the labeled interval after the last antibiotic dose (typically 2 to 4 days).
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Aztreonam
Perguntas frequentes
Can I take Aztreonam with Microbiota?
MediHelp rates the interaction as moderate. Aztreonam and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores intended to recolonize the gut. Systemic antibiotics may reduce spore viability and blunt the preventive effect against recurrent Clostridioides difficile infection, although aztreonam has a narrow Gram-negative spectrum so the effect is likely smaller.
How serious is the interaction between Aztreonam and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course before starting oral microbiota therapy, and keep the labeled interval after the last antibiotic dose (typically 2 to 4 days).
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Aztreonam page.
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