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Interações medicamentosas

Amoxicillin-clavulanic acid + Aztreonam

Gravidade: Leve

Amoxicillin-clavulanic acid and Aztreonam: minor interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Aztreonam combined with a beta-lactam or beta-lactamase inhibitor may give additive or synergistic activity against some Gram-negative organisms. This is a potentially beneficial effect, not a safety concern.

O que esta interação significa em palavras simples

Amoxicillin-clavulanic acid and Aztreonam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amoxicillin-clavulanic acid belongs to Anti Bacterial; Aztreonam belongs to Anti Bacterial.

Nível de evidência: Low

Por que acontece

Complementary binding to different penicillin-binding proteins, with clavulanate protecting against some beta-lactamases.

O que fazer

No safety monitoring is needed. Choose the regimen according to culture and susceptibility results.

O que perguntar ao farmacêutico

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

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Perguntas frequentes

Can I take Amoxicillin-clavulanic acid with Aztreonam?

MediHelp rates the interaction as minor. Amoxicillin-clavulanic acid and Aztreonam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aztreonam combined with a beta-lactam or beta-lactamase inhibitor may give additive or synergistic activity against some Gram-negative organisms. This is a potentially beneficial effect, not a safety concern.

How serious is the interaction between Amoxicillin-clavulanic acid and Aztreonam?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No safety monitoring is needed. Choose the regimen according to culture and susceptibility results.

What other medicines interact with Amoxicillin-clavulanic acid?

MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.

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