Interações medicamentosas
Bcg intravesical live + Cilastatin-imipenem
Gravidade: Moderada
Bcg intravesical live and Cilastatin-imipenem: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Intravesical BCG is a live attenuated mycobacterium that must remain viable to act. Systemic antibiotics, particularly those with antimycobacterial activity, may reduce its effect. Imipenem has limited mycobacterial activity, but BCG labeling advises postponing unnecessary antimicrobials.
O que esta interação significa em palavras simples
Bcg intravesical live and Cilastatin-imipenem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity may reduce the viability and local immune-stimulating effect of live BCG.
O que fazer
Defer elective antibiotic therapy during BCG instillations where possible. If an infection requires imipenem, consider holding the instillation until treatment is complete.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Bcg intravesical live e Cilastatin-imipenem, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Cilastatin-imipenem
Perguntas frequentes
Can I take Bcg intravesical live with Cilastatin-imipenem?
MediHelp rates the interaction as moderate. Bcg intravesical live and Cilastatin-imipenem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravesical BCG is a live attenuated mycobacterium that must remain viable to act. Systemic antibiotics, particularly those with antimycobacterial activity, may reduce its effect. Imipenem has limited mycobacterial activity, but BCG labeling advises postponing unnecessary antimicrobials.
How serious is the interaction between Bcg intravesical live and Cilastatin-imipenem?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer elective antibiotic therapy during BCG instillations where possible. If an infection requires imipenem, consider holding the instillation until treatment is complete.
What other medicines interact with Cilastatin-imipenem?
MediHelp also lists interactions of Cilastatin-imipenem with, for example, Divalproex, Ganciclovir, Valproic acid. The full list is on the Cilastatin-imipenem page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
