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Interações medicamentosas

Bcg vaccine live + Cefalexin

Gravidade: Moderada

Bcg vaccine live and Cefalexin: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Cefalexin has limited activity against BCG, but concurrent antibiotics are generally avoided around live bacterial vaccination.

O que esta interação significa em palavras simples

Bcg vaccine live and Cefalexin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Low

Por que acontece

Antibacterial activity may reduce replication of the live vaccine organism, lessening the immune response.

O que fazer

Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Bcg vaccine live with Cefalexin?

MediHelp rates the interaction as moderate. Bcg vaccine live and Cefalexin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Cefalexin has limited activity against BCG, but concurrent antibiotics are generally avoided around live bacterial vaccination.

How serious is the interaction between Bcg vaccine live and Cefalexin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.

What other medicines interact with Cefalexin?

MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.

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