Interações medicamentosas
Bcg vaccine live + Mercaptopurine
Gravidade: Contraindicada
Bcg vaccine live and Mercaptopurine: contraindicated interaction.
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Resumo
Immunosuppression from mercaptopurine can permit disseminated BCG infection. The vaccine response may also be inadequate.
O que esta interação significa em palavras simples
Bcg vaccine live and Mercaptopurine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Immunosuppression impairs control of live attenuated mycobacteria.
O que fazer
Do not give BCG vaccine to patients on mercaptopurine. Defer vaccination until immunosuppressive therapy has been discontinued for an appropriate interval.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Mercaptopurine
- Adenovirus types 4 and 7 live + Mercaptopurine Contraindicada
- Azathioprine + Mercaptopurine Contraindicada
- Febuxostat + Mercaptopurine Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Mercaptopurine Contraindicada
- Mercaptopurine + Smallpox vaccine live Contraindicada
- Adalimumab + Mercaptopurine Grave
Perguntas frequentes
Can I take Bcg vaccine live with Mercaptopurine?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Mercaptopurine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Immunosuppression from mercaptopurine can permit disseminated BCG infection. The vaccine response may also be inadequate.
How serious is the interaction between Bcg vaccine live and Mercaptopurine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG vaccine to patients on mercaptopurine. Defer vaccination until immunosuppressive therapy has been discontinued for an appropriate interval.
What other medicines interact with Mercaptopurine?
MediHelp also lists interactions of Mercaptopurine with, for example, Adenovirus types 4 and 7 live, Azathioprine, Febuxostat. The full list is on the Mercaptopurine page.
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