Interações medicamentosas
Bcg vaccine live + Tigecycline
Gravidade: Moderada
Bcg vaccine live and Tigecycline: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Antibiotics with activity against the vaccine organism may reduce the viability of live BCG and blunt the immune response. Tigecycline has activity against some mycobacteria, so vaccine effectiveness could be reduced during therapy.
O que esta interação significa em palavras simples
Bcg vaccine live and Tigecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity against the live attenuated organism may reduce replication and immunogenicity of the vaccine.
O que fazer
Give BCG vaccine before starting the antibiotic or after the course is complete. If antibiotic therapy is unavoidable, consider delaying vaccination.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Tigecycline
Perguntas frequentes
Can I take Bcg vaccine live with Tigecycline?
MediHelp rates the interaction as moderate. Bcg vaccine live and Tigecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antibiotics with activity against the vaccine organism may reduce the viability of live BCG and blunt the immune response. Tigecycline has activity against some mycobacteria, so vaccine effectiveness could be reduced during therapy.
How serious is the interaction between Bcg vaccine live and Tigecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give BCG vaccine before starting the antibiotic or after the course is complete. If antibiotic therapy is unavoidable, consider delaying vaccination.
What other medicines interact with Tigecycline?
MediHelp also lists interactions of Tigecycline with, for example, Typhoid vaccine live, Cholera vaccine, Microbiota. The full list is on the Tigecycline page.
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