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Interações medicamentosas

Carbonyl iron + Liothyronine

Gravidade: Moderada

Carbonyl iron and Liothyronine: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Oral iron can bind liothyronine in the gut and reduce its absorption. This may lead to loss of thyroid hormone effect and higher TSH.

O que esta interação significa em palavras simples

Carbonyl iron and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Carbonyl iron belongs to Miscellaneous; Liothyronine belongs to Endocrine.

Nível de evidência: Moderate

Por que acontece

Iron forms insoluble complexes with thyroid hormone in the gastrointestinal tract, reducing absorption.

O que fazer

Separate administration by at least 4 hours. Monitor TSH and clinical status after iron is started or stopped.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Carbonyl iron with Liothyronine?

MediHelp rates the interaction as moderate. Carbonyl iron and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron can bind liothyronine in the gut and reduce its absorption. This may lead to loss of thyroid hormone effect and higher TSH.

How serious is the interaction between Carbonyl iron and Liothyronine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by at least 4 hours. Monitor TSH and clinical status after iron is started or stopped.

What other medicines interact with Carbonyl iron?

MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.

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