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Interações medicamentosas

Cefepime + Cholera vaccine

Gravidade: Moderada

Cefepime and Cholera vaccine: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Oral cholera vaccine is a live attenuated bacterial strain that must replicate in the gut to induce immunity. Systemic antibiotics reaching the gut may reduce the strain's viability and weaken the immune response.

O que esta interação significa em palavras simples

Cefepime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Moderate

Por que acontece

The antibacterial activity can reduce replication of the live attenuated vaccine strain.

O que fazer

Do not give the vaccine to patients who received oral or parenteral antibiotics in the preceding 14 days; delay vaccination until after this interval.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Cefepime with Cholera vaccine?

MediHelp rates the interaction as moderate. Cefepime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral cholera vaccine is a live attenuated bacterial strain that must replicate in the gut to induce immunity. Systemic antibiotics reaching the gut may reduce the strain's viability and weaken the immune response.

How serious is the interaction between Cefepime and Cholera vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine to patients who received oral or parenteral antibiotics in the preceding 14 days; delay vaccination until after this interval.

What other medicines interact with Cefepime?

MediHelp also lists interactions of Cefepime with, for example, Amikacin, Dexamethasone-tobramycin, Gentamicin. The full list is on the Cefepime page.

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