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Interações medicamentosas

Chlordiazepoxide + Teduglutide

Gravidade: Moderada

Chlordiazepoxide and Teduglutide: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Teduglutide improves intestinal fluid and nutrient absorption and may increase absorption of oral drugs. Chlordiazepoxide exposure and sedation could therefore be higher than expected.

O que esta interação significa em palavras simples

Chlordiazepoxide and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Chlordiazepoxide belongs to Central Nervous System; Teduglutide belongs to Endocrine.

Nível de evidência: Low

Por que acontece

Teduglutide's enhancement of intestinal absorptive capacity may increase oral chlordiazepoxide absorption.

O que fazer

Monitor for increased sedation when teduglutide is started and reduce the chlordiazepoxide dose if needed.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Chlordiazepoxide with Teduglutide?

MediHelp rates the interaction as moderate. Chlordiazepoxide and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide improves intestinal fluid and nutrient absorption and may increase absorption of oral drugs. Chlordiazepoxide exposure and sedation could therefore be higher than expected.

How serious is the interaction between Chlordiazepoxide and Teduglutide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased sedation when teduglutide is started and reduce the chlordiazepoxide dose if needed.

What other medicines interact with Chlordiazepoxide?

MediHelp also lists interactions of Chlordiazepoxide with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide page.

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