Interações medicamentosas
Copper + Penicillamine
Gravidade: Moderada
Copper and Penicillamine: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
O que esta interação significa em palavras simples
Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
Por que acontece
Pharmacodynamic antagonism, since penicillamine chelates copper and promotes its urinary excretion.
O que fazer
Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Penicillamine
- Gold sodium thiomalate + Penicillamine Grave
- Aluminum hydroxide + Penicillamine Moderada
- Calcium carbonate + Penicillamine Moderada
- Calcium + Penicillamine Moderada
- Carbonyl iron + Penicillamine Moderada
- Digoxin + Penicillamine Moderada
Outras interações de Copper
- Copper + Omadacycline Moderada
- Copper + Sarecycline Moderada
- Copper + Trientine Moderada
- Ascorbic acid + Copper Leve
- Baloxavir marboxil + Copper Leve
- Copper + Vitamin c Leve
Perguntas frequentes
Can I take Copper with Penicillamine?
MediHelp rates the interaction as moderate. Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
How serious is the interaction between Copper and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
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