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Interações medicamentosas

Copper + Trientine

Gravidade: Moderada

Copper and Trientine: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Trientine chelates copper and promotes its elimination, which is the intended therapeutic effect in Wilson's disease. Copper supplementation would oppose this, and excessive treatment can cause copper deficiency.

O que esta interação significa em palavras simples

Copper and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Copper belongs to Gastrointestinal Tract; Trientine belongs to Miscellaneous.

Nível de evidência: High

Por que acontece

Trientine chelates copper, increasing urinary excretion and limiting absorption.

O que fazer

Avoid copper supplements in patients treated with trientine for Wilson's disease. Monitor serum and urinary copper and watch for over-treatment such as anemia.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Copper with Trientine?

MediHelp rates the interaction as moderate. Copper and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Trientine chelates copper and promotes its elimination, which is the intended therapeutic effect in Wilson's disease. Copper supplementation would oppose this, and excessive treatment can cause copper deficiency.

How serious is the interaction between Copper and Trientine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with trientine for Wilson's disease. Monitor serum and urinary copper and watch for over-treatment such as anemia.

What other medicines interact with Copper?

MediHelp also lists interactions of Copper with, for example, Omadacycline, Penicillamine, Sarecycline. The full list is on the Copper page.

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