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Interações medicamentosas

Cyclosporin + Oritavancin

Gravidade: Leve

Cyclosporin and Oritavancin: minor interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.

O que esta interação significa em palavras simples

Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cyclosporin belongs to Miscellaneous; Oritavancin belongs to Anti Bacterial.

Nível de evidência: Low

Por que acontece

Weak induction of CYP3A4 by oritavancin may modestly increase cyclosporine metabolism.

O que fazer

Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.

O que perguntar ao farmacêutico

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Cyclosporin with Oritavancin?

MediHelp rates the interaction as minor. Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.

How serious is the interaction between Cyclosporin and Oritavancin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.

What other medicines interact with Cyclosporin?

MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.

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