Interações medicamentosas
Deflazacort + Influenza virus vaccine quadrivalent intranasal
Gravidade: Contraindicada
Deflazacort and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
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Resumo
The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
O que esta interação significa em palavras simples
Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression impairs clearance of live attenuated virus and the vaccine immune response.
O que fazer
Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicada
- Bcg vaccine live + Deflazacort Contraindicada
- Deflazacort + Measles mumps and rubella vaccine Contraindicada
- Deflazacort + Measles mumps and rubella vaccine live Contraindicada
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicada
- Deflazacort + Measles vaccine Contraindicada
Perguntas frequentes
Can I take Deflazacort with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
How serious is the interaction between Deflazacort and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine. The full list is on the Deflazacort page.
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