Interações medicamentosas
Deflazacort + Measles mumps rubella and varicella vaccine live
Gravidade: Contraindicada
Deflazacort and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
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O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.
O que esta interação significa em palavras simples
Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.
O que fazer
Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicada
- Bcg vaccine live + Deflazacort Contraindicada
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Deflazacort + Measles mumps and rubella vaccine Contraindicada
- Deflazacort + Measles mumps and rubella vaccine live Contraindicada
- Deflazacort + Measles vaccine Contraindicada
Perguntas frequentes
Can I take Deflazacort with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.
How serious is the interaction between Deflazacort and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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