Interações medicamentosas
Deflazacort + Measles vaccine
Gravidade: Contraindicada
Deflazacort and Measles vaccine: contraindicated interaction.
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Resumo
Measles vaccine contains live attenuated virus that may cause disseminated disease in a patient immunosuppressed by deflazacort. The vaccine response may also be inadequate.
O que esta interação significa em palavras simples
Deflazacort and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts immunity.
O que fazer
Do not give at immunosuppressive doses; vaccinate at least the labeled interval after stopping steroids, or before starting them. For exposure, consider immunoglobulin rather than vaccine.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicada
- Bcg vaccine live + Deflazacort Contraindicada
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Deflazacort + Measles mumps and rubella vaccine Contraindicada
- Deflazacort + Measles mumps and rubella vaccine live Contraindicada
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicada
Perguntas frequentes
Can I take Deflazacort with Measles vaccine?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine contains live attenuated virus that may cause disseminated disease in a patient immunosuppressed by deflazacort. The vaccine response may also be inadequate.
How serious is the interaction between Deflazacort and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give at immunosuppressive doses; vaccinate at least the labeled interval after stopping steroids, or before starting them. For exposure, consider immunoglobulin rather than vaccine.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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