Interações medicamentosas
Deflazacort + Measles mumps and rubella vaccine live
Gravidade: Contraindicada
Deflazacort and Measles mumps and rubella vaccine live: contraindicated interaction.
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Resumo
The live attenuated MMR viruses may replicate excessively in patients immunosuppressed by deflazacort, risking vaccine-strain disease. The immune response may also be reduced.
O que esta interação significa em palavras simples
Deflazacort and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.
O que fazer
Avoid during immunosuppressive corticosteroid therapy; give at least four weeks before starting steroids or after stopping for the interval in labeling. Check immunity and consider immunoglobulin after exposure.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicada
- Bcg vaccine live + Deflazacort Contraindicada
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Deflazacort + Measles mumps and rubella vaccine Contraindicada
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicada
- Deflazacort + Measles vaccine Contraindicada
Perguntas frequentes
Can I take Deflazacort with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated MMR viruses may replicate excessively in patients immunosuppressed by deflazacort, risking vaccine-strain disease. The immune response may also be reduced.
How serious is the interaction between Deflazacort and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during immunosuppressive corticosteroid therapy; give at least four weeks before starting steroids or after stopping for the interval in labeling. Check immunity and consider immunoglobulin after exposure.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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