Interações medicamentosas
Dexamethasone-neomycin-polymyxin + Moxifloxacin
Gravidade: Grave
Dexamethasone-neomycin-polymyxin and Moxifloxacin: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Fluoroquinolones given with systemic corticosteroids increase the risk of tendinitis and tendon rupture. Older age and long treatment raise the risk further.
O que esta interação significa em palavras simples
Dexamethasone-neomycin-polymyxin and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexamethasone-neomycin-polymyxin belongs to Anti Bacterial; Moxifloxacin belongs to Anti Bacterial.
Por que acontece
Additive tendon toxicity from fluoroquinolone effects on tenocytes and corticosteroid impairment of collagen synthesis.
O que fazer
Avoid the combination in older patients where an alternative antibiotic exists. Discontinue moxifloxacin at the first sign of tendon pain.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Dexamethasone-neomycin-polymyxin
- Dexamethasone-neomycin-polymyxin + Ketorolac Grave
- Dexamethasone-neomycin-polymyxin + Lapatinib Grave
- Dexamethasone-neomycin-polymyxin + Levofloxacin Grave
- Dexamethasone-neomycin-polymyxin + Mifepristone Grave
- Aldesleukin + Dexamethasone-neomycin-polymyxin Moderada
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Dexamethasone-neomycin-polymyxin Moderada
Outras interações de Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicada
- Arsenic trioxide + Moxifloxacin Contraindicada
- Disopyramide + Moxifloxacin Contraindicada
- Dofetilide + Moxifloxacin Contraindicada
- Dronedarone + Moxifloxacin Contraindicada
- Droperidol + Moxifloxacin Contraindicada
Perguntas frequentes
Can I take Dexamethasone-neomycin-polymyxin with Moxifloxacin?
MediHelp rates the interaction as major. Dexamethasone-neomycin-polymyxin and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fluoroquinolones given with systemic corticosteroids increase the risk of tendinitis and tendon rupture. Older age and long treatment raise the risk further.
How serious is the interaction between Dexamethasone-neomycin-polymyxin and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in older patients where an alternative antibiotic exists. Discontinue moxifloxacin at the first sign of tendon pain.
What other medicines interact with Dexamethasone-neomycin-polymyxin?
MediHelp also lists interactions of Dexamethasone-neomycin-polymyxin with, for example, Ketorolac, Lapatinib, Levofloxacin. The full list is on the Dexamethasone-neomycin-polymyxin page.
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