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Interações medicamentosas

Dicyclomine + Revefenacin

Gravidade: Moderada

Dicyclomine and Revefenacin: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Revefenacin is an inhaled long-acting muscarinic antagonist with low systemic exposure. Combined with oral dicyclomine, additive anticholinergic effects may occur, such as dry mouth, urinary retention and constipation.

O que esta interação significa em palavras simples

Dicyclomine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dicyclomine belongs to Respiratory; Revefenacin belongs to Respiratory.

Nível de evidência: Low

Por que acontece

Additive antimuscarinic effects at peripheral cholinergic receptors.

O que fazer

Monitor for urinary retention, constipation, dry mouth and narrow-angle glaucoma symptoms. Reduce or stop dicyclomine if anticholinergic effects develop.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Dicyclomine with Revefenacin?

MediHelp rates the interaction as moderate. Dicyclomine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Revefenacin is an inhaled long-acting muscarinic antagonist with low systemic exposure. Combined with oral dicyclomine, additive anticholinergic effects may occur, such as dry mouth, urinary retention and constipation.

How serious is the interaction between Dicyclomine and Revefenacin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation, dry mouth and narrow-angle glaucoma symptoms. Reduce or stop dicyclomine if anticholinergic effects develop.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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