Interações medicamentosas
Indacaterol-glycopyrronium + Revefenacin
Gravidade: Grave
Indacaterol-glycopyrronium and Revefenacin: major interaction.
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Resumo
Revefenacin is an inhaled long-acting muscarinic antagonist, as is glycopyrronium, so the two duplicate anticholinergic therapy. Combined use may increase dry mouth, urinary retention, constipation, glaucoma risk and tachycardia.
O que esta interação significa em palavras simples
Indacaterol-glycopyrronium and Revefenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Indacaterol-glycopyrronium belongs to Respiratory; Revefenacin belongs to Respiratory.
Por que acontece
Additive antimuscarinic effects from two long-acting muscarinic antagonists.
O que fazer
Avoid using two long-acting anticholinergics together and pick a single LAMA-containing regimen. Monitor for anticholinergic effects if the overlap occurs during a switch.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Indacaterol-glycopyrronium
Outras interações de Revefenacin
- Cyclosporin + Revefenacin Grave
- Revefenacin + Rifampicin Grave
- Revefenacin + Tiotropium Grave
- Atropine + Revefenacin Moderada
- Benztropine + Revefenacin Moderada
- Darifenacin + Revefenacin Moderada
Perguntas frequentes
Can I take Indacaterol-glycopyrronium with Revefenacin?
MediHelp rates the interaction as major. Indacaterol-glycopyrronium and Revefenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Revefenacin is an inhaled long-acting muscarinic antagonist, as is glycopyrronium, so the two duplicate anticholinergic therapy. Combined use may increase dry mouth, urinary retention, constipation, glaucoma risk and tachycardia.
How serious is the interaction between Indacaterol-glycopyrronium and Revefenacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two long-acting anticholinergics together and pick a single LAMA-containing regimen. Monitor for anticholinergic effects if the overlap occurs during a switch.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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