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Interações medicamentosas

Dihydroergotamine intranasal + Dopamine

Gravidade: Contraindicada

Dihydroergotamine intranasal and Dopamine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Intranasal dihydroergotamine is systemically absorbed and, together with dopamine, can cause additive vasoconstriction. This may produce severe hypertension and peripheral or cerebral ischemia.

O que esta interação significa em palavras simples

Dihydroergotamine intranasal and Dopamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

Additive vasoconstriction from ergot alkaloid activity and dopamine adrenergic effects.

O que fazer

Avoid concurrent use. Use a different migraine therapy while dopamine is required.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

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Perguntas frequentes

Can I take Dihydroergotamine intranasal with Dopamine?

MediHelp rates the interaction as contraindicated. Dihydroergotamine intranasal and Dopamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intranasal dihydroergotamine is systemically absorbed and, together with dopamine, can cause additive vasoconstriction. This may produce severe hypertension and peripheral or cerebral ischemia.

How serious is the interaction between Dihydroergotamine intranasal and Dopamine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use. Use a different migraine therapy while dopamine is required.

What other medicines interact with Dopamine?

MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine, Selegiline transdermal, Amitriptyline. The full list is on the Dopamine page.

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