Interações medicamentosas
Dopamine + Selegiline transdermal
Gravidade: Contraindicada
Dopamine and Selegiline transdermal: contraindicated interaction.
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Resumo
Selegiline is a monoamine oxidase inhibitor, and inhibited MAO greatly potentiates the pressor effect of dopamine. This may cause severe hypertensive crisis.
O que esta interação significa em palavras simples
Dopamine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
MAO inhibition reduces dopamine breakdown and increases norepinephrine stores, amplifying sympathomimetic effects.
O que fazer
Avoid; if dopamine is essential, stop selegiline and use a markedly reduced starting dose with close blood pressure monitoring only in an emergency.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicada
- Dihydroergotamine + Dopamine Contraindicada
- Amitriptyline + Dopamine Grave
- Clomipramine + Dopamine Grave
- Desipramine + Dopamine Grave
- Dextroamphetamine + Dopamine Grave
Perguntas frequentes
Can I take Dopamine with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Dopamine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Selegiline is a monoamine oxidase inhibitor, and inhibited MAO greatly potentiates the pressor effect of dopamine. This may cause severe hypertensive crisis.
How serious is the interaction between Dopamine and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if dopamine is essential, stop selegiline and use a markedly reduced starting dose with close blood pressure monitoring only in an emergency.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Amitriptyline. The full list is on the Dopamine page.
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