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Interações medicamentosas

Dihydroergotamine + Dopamine

Gravidade: Contraindicada

Dihydroergotamine and Dopamine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Both agents cause vasoconstriction, and combined use can produce severe peripheral and cerebral vasospasm with marked hypertension. Ischemic complications have been described with ergot alkaloids and pressor agents.

O que esta interação significa em palavras simples

Dihydroergotamine and Dopamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dihydroergotamine belongs to Central Nervous System; Dopamine belongs to Cardiovascular.

Nível de evidência: Moderate

Por que acontece

Additive alpha-adrenergic and direct vascular smooth muscle vasoconstriction.

O que fazer

Avoid combining; use a non-ergot therapy for migraine in patients needing dopamine. If it occurs, monitor perfusion and blood pressure closely.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Dihydroergotamine with Dopamine?

MediHelp rates the interaction as contraindicated. Dihydroergotamine and Dopamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents cause vasoconstriction, and combined use can produce severe peripheral and cerebral vasospasm with marked hypertension. Ischemic complications have been described with ergot alkaloids and pressor agents.

How serious is the interaction between Dihydroergotamine and Dopamine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining; use a non-ergot therapy for migraine in patients needing dopamine. If it occurs, monitor perfusion and blood pressure closely.

What other medicines interact with Dopamine?

MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Selegiline transdermal, Amitriptyline. The full list is on the Dopamine page.

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