Interações medicamentosas
Insulin glulisine + Rosiglitazone
Gravidade: Grave
Insulin glulisine and Rosiglitazone: major interaction.
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Resumo
Rosiglitazone with insulin raises the risk of hypoglycemia and of edema and congestive heart failure. Combined use is generally discouraged because of the cardiovascular fluid-retention risk.
O que esta interação significa em palavras simples
Insulin glulisine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin glulisine belongs to Endocrine; Rosiglitazone belongs to Endocrine.
Por que acontece
Rosiglitazone increases insulin sensitivity, adding to insulin effect, and both promote sodium and fluid retention.
O que fazer
Avoid in patients with heart failure risk and monitor for edema, rapid weight gain and dyspnea. Reduce insulin if hypoglycemia occurs.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Insulin glulisine
Outras interações de Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Grave
- Insulin aspart-insulin aspart protamine + Rosiglitazone Grave
- Insulin aspart + Rosiglitazone Grave
- Insulin degludec / insulin aspart + Rosiglitazone Grave
- Insulin degludec-insulin aspart + Rosiglitazone Grave
- Insulin degludec-liraglutide + Rosiglitazone Grave
Perguntas frequentes
Can I take Insulin glulisine with Rosiglitazone?
MediHelp rates the interaction as major. Insulin glulisine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin raises the risk of hypoglycemia and of edema and congestive heart failure. Combined use is generally discouraged because of the cardiovascular fluid-retention risk.
How serious is the interaction between Insulin glulisine and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with heart failure risk and monitor for edema, rapid weight gain and dyspnea. Reduce insulin if hypoglycemia occurs.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
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