Interações medicamentosas
Iodinated glycerol + Propylthiouracil
Gravidade: Moderada
Iodinated glycerol and Propylthiouracil: moderate interaction.
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Resumo
Iodinated glycerol is an iodine-containing expectorant that delivers iodide systemically. Iodide can alter thyroid function and may add to or interfere with antithyroid therapy, with possible goiter or hypothyroidism.
O que esta interação significa em palavras simples
Iodinated glycerol and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Iodide load affects thyroid hormone synthesis and release, producing additive thyroid suppression.
O que fazer
Avoid iodine-containing expectorants where possible, and monitor TSH and free T4 if they are used.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Propylthiouracil
Perguntas frequentes
Can I take Iodinated glycerol with Propylthiouracil?
MediHelp rates the interaction as moderate. Iodinated glycerol and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iodinated glycerol is an iodine-containing expectorant that delivers iodide systemically. Iodide can alter thyroid function and may add to or interfere with antithyroid therapy, with possible goiter or hypothyroidism.
How serious is the interaction between Iodinated glycerol and Propylthiouracil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid iodine-containing expectorants where possible, and monitor TSH and free T4 if they are used.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
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