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Interações medicamentosas

Levothyroxine + Patiromer

Gravidade: Moderada

Levothyroxine and Patiromer: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Patiromer is a non-absorbed polymer that can bind co-administered oral drugs in the gut, reducing levothyroxine absorption. This may lead to under-replacement of thyroid hormone.

O que esta interação significa em palavras simples

Levothyroxine and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Levothyroxine belongs to Endocrine; Patiromer belongs to Miscellaneous.

Nível de evidência: Moderate

Por que acontece

Patiromer binds levothyroxine in the gastrointestinal tract, reducing its absorption.

O que fazer

Give levothyroxine at least 3 hours before or after patiromer. Monitor TSH when therapy is started or changed.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Levothyroxine with Patiromer?

MediHelp rates the interaction as moderate. Levothyroxine and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patiromer is a non-absorbed polymer that can bind co-administered oral drugs in the gut, reducing levothyroxine absorption. This may lead to under-replacement of thyroid hormone.

How serious is the interaction between Levothyroxine and Patiromer?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give levothyroxine at least 3 hours before or after patiromer. Monitor TSH when therapy is started or changed.

What other medicines interact with Levothyroxine?

MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.

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