Interações medicamentosas
Micafungin + Saccharomyces boulardii
Gravidade: Moderada
Micafungin and Saccharomyces boulardii: moderate interaction.
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Resumo
Micafungin has activity against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also caused fungemia in critically ill or catheterized patients.
O que esta interação significa em palavras simples
Micafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Pharmacodynamic antagonism: antifungal activity against the live yeast probiotic.
O que fazer
Avoid the probiotic during systemic antifungal therapy, particularly in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Micafungin
- Lomitapide + Micafungin Moderada
- Micafungin + Sirolimus Moderada
- Avapritinib + Micafungin Leve
- Finerenone + Micafungin Leve
- Isavuconazonium + Micafungin Leve
- Ivacaftor + Micafungin Leve
Perguntas frequentes
Can I take Micafungin with Saccharomyces boulardii?
MediHelp rates the interaction as moderate. Micafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Micafungin has activity against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also caused fungemia in critically ill or catheterized patients.
How serious is the interaction between Micafungin and Saccharomyces boulardii?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the probiotic during systemic antifungal therapy, particularly in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Sirolimus, Avapritinib. The full list is on the Micafungin page.
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