Interações medicamentosas
Tetracycline + Typhoid vaccine live
Gravidade: Grave
Tetracycline and Typhoid vaccine live: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Oral live attenuated typhoid vaccine (Ty21a) is a viable bacterial strain that antibiotics can inactivate, reducing the immune response and protection. Tetracyclines are active against Salmonella, so vaccine failure is possible.
O que esta interação significa em palavras simples
Tetracycline and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Antibacterial activity kills or inhibits the live attenuated Salmonella strain, reducing colonisation and immunogenicity.
O que fazer
Avoid antibiotics from at least 3 days before until after completing the vaccine course, per labeling. If antibiotics are required, delay vaccination or use the inactivated injectable vaccine.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Tetracycline
- Acitretin + Tetracycline Contraindicada
- Methoxyflurane + Tetracycline Contraindicada
- Isotretinoin + Tetracycline Grave
- Palovarotene + Tetracycline Grave
- Strontium ranelate + Tetracycline Grave
- Tetracycline + Tretinoin Grave
Perguntas frequentes
Can I take Tetracycline with Typhoid vaccine live?
MediHelp rates the interaction as major. Tetracycline and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral live attenuated typhoid vaccine (Ty21a) is a viable bacterial strain that antibiotics can inactivate, reducing the immune response and protection. Tetracyclines are active against Salmonella, so vaccine failure is possible.
How serious is the interaction between Tetracycline and Typhoid vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid antibiotics from at least 3 days before until after completing the vaccine course, per labeling. If antibiotics are required, delay vaccination or use the inactivated injectable vaccine.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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