Interações medicamentosas
Methoxyflurane + Tetracycline
Gravidade: Contraindicada
Methoxyflurane and Tetracycline: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
O que esta interação significa em palavras simples
Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive nephrotoxicity from methoxyflurane fluoride metabolites and tetracycline-related renal impairment.
O que fazer
Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Methoxyflurane e Tetracycline, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Tetracycline
- Acitretin + Tetracycline Contraindicada
- Isotretinoin + Tetracycline Grave
- Palovarotene + Tetracycline Grave
- Strontium ranelate + Tetracycline Grave
- Tetracycline + Tretinoin Grave
- Tetracycline + Typhoid vaccine live Grave
Perguntas frequentes
Can I take Methoxyflurane with Tetracycline?
MediHelp rates the interaction as contraindicated. Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
How serious is the interaction between Methoxyflurane and Tetracycline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Isotretinoin, Palovarotene. The full list is on the Tetracycline page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
