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Dapsone

Dapsone is a medicine in the class anti bacterial. It is used for acne.

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僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Anti Bacterial
常見劑型
錠劑, 凝膠
常見規格
100 mg, 50 mg, 75 mg/g
已知交互作用
139 (嚴重: 2 · 中度: 60 · 輕微: 77)
商品名
5
國家與市場
3

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Sulfone; prevents normal bacterial utilization of para-aminobenzoic acid (PABA) for the synthesis of folic acid by acting as a competitive antagonist of PABA; it is bactericidal and bacteriostatic against Mycobacterium leprae

成人常用劑量（仿單摘要）

Leprosy: 100 mg PO qDay, in combination with other antileprosy drugs

僅摘錄仿單中第一行劑量說明；完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Safe Long use (leprosy, malaria, PCP prophylaxis, skin disease) shows no clear rise in birth defects. It can cause haemolysis in the mother and, near term, haemolysis and jaundice in the newborn, especially with G6PD deficiency. Gel: low absorption. Use when needed.
哺乳
Unsafe Oral: passes into milk (about 10% of the maternal dose); mild haemolytic anaemia occurred in one infant. Gel: low absorption. LactMed: can be used, but monitor for haemolysis and jaundice, especially in newborns and G6PD deficiency.

已通報的副作用

  • Headache
  • Insomnia
  • Hemolysis
  • Methemoglobinemia

禁忌症

  • Hypersensitivity to drug or component

哪些人需要特別留意

  • Peripheral neuropathy may occur
  • Toxic epidermal necrolysis and other dermatologic reactions may occur
  • Use caution when treating patients with hypersensitivity to sulfonamides

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。

重要交互作用 (139)

All 139 interactions, with severity and what to do

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解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可開啟 Dapsone 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Paediatric dosing
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions
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同類別的其他藥品

常見問題

What is Dapsone used for?

Dapsone is a medicine in the class anti bacterial. It is used for Acne, Dermatitis herpetiformis, Lepromatous disease.

What side effects have been reported with Dapsone?

Headache, Insomnia, Hemolysis, Methemoglobinemia.

Can Dapsone be taken in pregnancy or while breastfeeding?

Pregnancy: Safe. Long use (leprosy, malaria, PCP prophylaxis, skin disease) shows no clear rise in birth defects. It can cause haemolysis in the mother and, near term, haemolysis and jaundice in the newborn, especially with G6PD deficiency. Gel: low absorption. Use when needed. Breastfeeding: Unsafe. Oral: passes into milk (about 10% of the maternal dose); mild haemolytic anaemia occurred in one infant. Gel: low absorption. LactMed: can be used, but monitor for haemolysis and jaundice, especially in newborns and G6PD deficiency.

What does Dapsone interact with?

MediHelp lists 139 known interactions for Dapsone. Major: 2 · Moderate: 60 · Minor: 77. The most serious include Bcg vaccine live, Primaquine, Apalutamide.

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