藥品參考
Eravacycline
Eravacycline is a medicine in the class anti bacterial. It is used for intra-abdominal infections.
- 藥物類別: Anti Bacterial
- 用途: intra-abdominal infections
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- ATC 代碼
- J01AA13
- 常見劑型
- 注射劑
- 已知交互作用
- 5 (中度: 5)
- 商品名
- 2
- 國家與市場
- 2
用途
作用方式
Eravacycline is an antibacterial drug (tetracycline class); the label gives no further mechanism detail.
成人常用劑量(仿單摘要)
Complicated intra-abdominal infection (adults 18 years and older): 1 mg/kg IV infusion over approximately 60 minutes every 12 hours for a total of 4 to 14 days, guided by severity, location and clinical response.
懷孕與哺乳
- 懷孕
- Unsafe May cause tooth discoloration and reversible inhibition of bone growth if given in the second and third trimester; limited human data. Tetracyclines can have toxic effects on the developing fetus.
- 哺乳
- Unsafe Not known if excreted in human milk; breastfeeding is not recommended during treatment and for 4 days after the last dose.
已通報的副作用
- Infusion site reactions
- Nausea
- Vomiting
- Diarrhea
- Hypotension
- Wound dehiscence
禁忌症
- Known hypersensitivity to eravacycline, tetracycline-class antibacterial drugs, or any excipients.
哪些人需要特別留意
- Life-threatening hypersensitivity (anaphylactic) reactions reported; avoid in patients with known tetracycline hypersensitivity and discontinue if an allergic reaction occurs.
- Use during tooth development (last half of pregnancy, infancy, childhood to age 8 years) may cause permanent tooth discoloration and enamel hypoplasia.
- Use during the second and third trimester of pregnancy, infancy and childhood up to age 8 years may cause reversible inhibition of bone growth.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。
重要交互作用 (5)
- Amoxicillin + Eravacycline Moderate
- Amoxicillin-clavulanic acid + Eravacycline Moderate
- Ampicillin + Eravacycline Moderate
- Ampicillin-sulbactam + Eravacycline Moderate
- Eravacycline + Warfarin Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用,即可開啟 Eravacycline 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
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同類別的其他藥品
常見問題
What is Eravacycline used for?
Eravacycline is a medicine in the class anti bacterial. It is used for Intra-abdominal infections.
What side effects have been reported with Eravacycline?
Infusion site reactions, Nausea, Vomiting, Diarrhea, Hypotension, Wound dehiscence.
Can Eravacycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause tooth discoloration and reversible inhibition of bone growth if given in the second and third trimester; limited human data. Tetracyclines can have toxic effects on the developing fetus. Breastfeeding: Unsafe. Not known if excreted in human milk; breastfeeding is not recommended during treatment and for 4 days after the last dose.
What does Eravacycline interact with?
MediHelp lists 5 known interactions for Eravacycline. Moderate: 5. The most serious include Amoxicillin, Amoxicillin-clavulanic acid, Ampicillin.
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