藥品參考
Omadacycline
Omadacycline is a medicine in the class anti bacterial. It is used for pneumonia.
- 藥物類別: Anti Bacterial
- 用途: pneumonia
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- 常見劑型
- 錠劑, 注射劑
- 已知交互作用
- 41 (禁忌併用: 1 · 嚴重: 2 · 中度: 28 · 輕微: 10)
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Omadacycline (NUZYRA) is an antibacterial drug. The provided label section gives no further mechanistic detail.
成人常用劑量（仿單摘要）
CABP (injection): loading 200 mg IV over 60 minutes on day 1, or 100 mg IV over 30 minutes twice on day 1; then 100 mg IV over 30 minutes once daily; duration 7 to 14 days
懷孕與哺乳
- 懷孕
- Unsafe May cause tooth discoloration and reversible bone growth inhibition in second and third trimester; animal studies showed fetal loss and malformations; may cause embryonic or fetal harm.
- 哺乳
- Unsafe Breastfeeding is not recommended during treatment and for 4 days after the last dose.
已通報的副作用
- Nausea
- Vomiting
- Infusion site reactions
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Headache
禁忌症
- Known hypersensitivity to omadacycline, tetracycline class antibacterial drugs, or any excipients.
哪些人需要特別留意
- Use during tooth development (last half of pregnancy, infancy, childhood up to age 8 years) may cause permanent tooth discoloration and enamel hypoplasia.
- May cause reversible inhibition of bone growth in the second and third trimester, infancy and childhood up to age 8 years.
- Hypersensitivity reactions reported; discontinue if an allergic reaction occurs.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (41)
- Acitretin + Omadacycline Contraindicated
- Isotretinoin + Omadacycline Major
- Omadacycline + Tretinoin Major
- Aluminum hydroxide + Omadacycline Moderate
- Amoxicillin + Omadacycline Moderate
- Amoxicillin-clavulanic acid + Omadacycline Moderate
- Ampicillin + Omadacycline Moderate
- Ampicillin-sulbactam + Omadacycline Moderate
- Benzathine penicillin g + Omadacycline Moderate
- Bismuth subsalicylate + Omadacycline Moderate
同類別的其他藥品
常見問題
What is Omadacycline used for?
Omadacycline is a medicine in the class anti bacterial. It is used for Pneumonia, Skin infections.
What side effects have been reported with Omadacycline?
Nausea, Vomiting, Infusion site reactions, Alanine aminotransferase increased, Aspartate aminotransferase increased, Headache.
Can Omadacycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause tooth discoloration and reversible bone growth inhibition in second and third trimester; animal studies showed fetal loss and malformations; may cause embryonic or fetal harm. Breastfeeding: Unsafe. Breastfeeding is not recommended during treatment and for 4 days after the last dose.
What does Omadacycline interact with?
MediHelp lists 41 known interactions for Omadacycline. Contraindicated: 1 · Major: 2 · Moderate: 28 · Minor: 10. The most serious include Acitretin, Isotretinoin, Tretinoin.
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