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藥品參考

Tetracycline

Tetracycline is a medicine in the class anti bacterial. It is used for acne.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Anti Bacterial
常見劑型
軟膏, 膠囊, 噴霧劑, 溶液, 注射劑
常見規格
250 mg, 30 mg/ml, 3%
已知交互作用
108 (禁忌併用: 2 · 嚴重: 5 · 中度: 72 · 輕微: 29)
商品名
29
國家與市場
4

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s)

成人常用劑量(仿單摘要)

Chronic Bronchitis, Acute Exacerbation (Usual daily dose): 500 mg PO q12hr or 250 mg PO q6hr (ie, 1000 mg/day)

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unsafe Tetracyclines can permanently stain the baby's teeth and affect bone growth once tooth mineralisation starts (about 15-16 weeks), and high doses have caused serious liver toxicity in pregnant women. Avoid in pregnancy; use a safer antibiotic. Skin or eye use gives little absorption.
哺乳
Safe Labels advise avoiding breastfeeding. LactMed is more reassuring: milk levels are low and milk calcium limits absorption, so short courses are probably acceptable; avoid prolonged or repeated courses. Watch the infant for rash, diarrhoea or thrush.

已通報的副作用

  • Nausea
  • Anorexia
  • Hemolytic anemia
  • Permanent discoloration of teeth
  • Increased BUN (dose-related)

禁忌症

  • Documented hypersensitivity
  • Severe hepatic dysfunction
  • Pregnancy 2nd and 3rd trimesters

哪些人需要特別留意

  • Consider drug serum level determinations in prolonged therapy
  • Antianabolic action of the tetracyclines may cause an increase in BUN; in patients with significantly impaired renal function.
  • Intracranial hypertension (IH, pseudotumor cerebri) has been associated with the use of tetracyclines

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

重要交互作用 (108)

All 108 interactions, with severity and what to do

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解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Tetracycline 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions

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同類別的其他藥品

常見問題

What is Tetracycline used for?

Tetracycline is a medicine in the class anti bacterial. It is used for Acne, Bronchitis, Brucellosis, Gonorrhea, Syphilis.

What side effects have been reported with Tetracycline?

Nausea, Anorexia, Hemolytic anemia, Permanent discoloration of teeth, Increased BUN (dose-related).

Can Tetracycline be taken in pregnancy or while breastfeeding?

Pregnancy: Unsafe. Tetracyclines can permanently stain the baby's teeth and affect bone growth once tooth mineralisation starts (about 15-16 weeks), and high doses have caused serious liver toxicity in pregnant women. Avoid in pregnancy; use a safer antibiotic. Skin or eye use gives little absorption. Breastfeeding: Safe. Labels advise avoiding breastfeeding. LactMed is more reassuring: milk levels are low and milk calcium limits absorption, so short courses are probably acceptable; avoid prolonged or repeated courses. Watch the infant for rash, diarrhoea or thrush.

What does Tetracycline interact with?

MediHelp lists 108 known interactions for Tetracycline. Contraindicated: 2 · Major: 5 · Moderate: 72 · Minor: 29. The most serious include Acitretin, Methoxyflurane, Isotretinoin.

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