藥品參考
Prucalopride
Prucalopride is a medicine in the class gastrointestinal tract. It is used for constipation.
- 藥物類別: Gastrointestinal Tract
- 用途: constipation
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Gastrointestinal Tract
- ATC 代碼
- A06AX05
- 常見劑型
- 錠劑
- 常見規格
- 2 mg, 1 mg
- 已知交互作用
- 1 (中度: 1)
- 商品名
- 16
- 國家與市場
- 5
用途
作用方式
Selective serotonin type 4 (5-HT4) receptor agonist; elicits GI prokinetic actions that stimulates colonic peristalsis (high-amplitude propagating contractions [HAPCs]), which increases bowel motility.
成人常用劑量（仿單摘要）
Chronic Idiopathic Constipation: 2 mg orally once a day.
懷孕與哺乳
- 懷孕
- Unknown Limited human data (case reports); no harm in rats or rabbits at 390 to 780 times the human dose. Miscarriages occurred in trials, link to the drug unclear. EU label: not recommended in pregnancy or without contraception. Prefer a better-studied laxative (bulk-forming, macrogol).
- 哺乳
- Unknown Passes into milk: about 6% of the mother's weight-adjusted dose in a US label study; no data on infant effects. UK label: no infant effects expected, but decide whether to stop breastfeeding or the drug; US label: weigh benefits. LactMed: monitor the infant for diarrhoea.
已通報的副作用
- Headache
- Diarrhea
- Nausea
- Abdominal pain
禁忌症
- Hypersensitivity
- Intestinal perforation or obstruction due to structural or functional disorder of gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract (eg, Crohn disease, ulcerative colitis, toxic megacolon/megarectum)
哪些人需要特別留意
- Suicidal ideation and behavior In clinical trials, suicides, suicide attempts, and suicidal ideation reported.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (1)
- Mosapride + Prucalopride Moderate
常見問題
What is Prucalopride used for?
Prucalopride is a medicine in the class gastrointestinal tract. It is used for Constipation.
What side effects have been reported with Prucalopride?
Headache, Diarrhea, Nausea, Abdominal pain.
Can Prucalopride be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data (case reports); no harm in rats or rabbits at 390 to 780 times the human dose. Miscarriages occurred in trials, link to the drug unclear. EU label: not recommended in pregnancy or without contraception. Prefer a better-studied laxative (bulk-forming, macrogol). Breastfeeding: Unknown. Passes into milk: about 6% of the mother's weight-adjusted dose in a US label study; no data on infant effects. UK label: no infant effects expected, but decide whether to stop breastfeeding or the drug; US label: weigh benefits. LactMed: monitor the infant for diarrhoea.
What does Prucalopride interact with?
MediHelp lists 1 known interactions for Prucalopride. Moderate: 1. The most serious include Mosapride.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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