藥品參考
Pyrilamine
Pyrilamine is a medicine in the class respiratory. It is used for allergic rhinitis.
- 藥物類別: Respiratory
- 用途: allergic rhinitis
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Respiratory
- 常見劑型
- 溶液
- 常見規格
- 12.5 mg/15 ml
- 已知交互作用
- 8 (中度: 2 · 輕微: 6)
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Pyrilamine (mepyramine) is a first-generation ethylenediamine-class antihistamine that acts as an inverse agonist (competitive antagonist) at histamine H1 receptors. It blocks histamine-mediated vasodilation, increased capillary permeability and sensory nerve stimulation, which reduces sneezing, rhinorrhoea and itching.
懷孕與哺乳
- 懷孕
- Unknown An older sedating antihistamine (mepyramine), often in cold or period-pain combinations. Human data are limited, with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine are preferred; avoid decongestant combinations early in pregnancy.
- 哺乳
- Safe Small, occasional doses are not expected to harm the infant (LactMed: probably acceptable). Larger or prolonged doses may sedate the infant or lower milk supply, especially with a decongestant such as pseudoephedrine or before lactation is established. Non-sedating antihistamines are preferred.
已通報的副作用
- Marked drowsiness
- Excitability, especially in children
哪些人需要特別留意
- Ask a doctor before use if the child has a breathing problem such as emphysema or chronic bronchitis.
- Ask a doctor before use if the child has glaucoma.
- Marked drowsiness may occur; excitability may occur, especially in children.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (8)
- Fentanyl + Pyrilamine Moderate
- Levetiracetam + Pyrilamine Moderate
- Amisulpride + Pyrilamine Minor
- Asenapine + Pyrilamine Minor
- Brexpiprazole + Pyrilamine Minor
- Brimonidine + Pyrilamine Minor
- Brivaracetam + Pyrilamine Minor
- Cariprazine + Pyrilamine Minor
同類別的其他藥品
常見問題
What is Pyrilamine used for?
Pyrilamine is a medicine in the class respiratory. It is used for Allergic rhinitis, Hay fever.
What side effects have been reported with Pyrilamine?
Marked drowsiness, Excitability, especially in children.
Can Pyrilamine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. An older sedating antihistamine (mepyramine), often in cold or period-pain combinations. Human data are limited, with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine are preferred; avoid decongestant combinations early in pregnancy. Breastfeeding: Safe. Small, occasional doses are not expected to harm the infant (LactMed: probably acceptable). Larger or prolonged doses may sedate the infant or lower milk supply, especially with a decongestant such as pseudoephedrine or before lactation is established. Non-sedating antihistamines are preferred.
What does Pyrilamine interact with?
MediHelp lists 8 known interactions for Pyrilamine. Moderate: 2 · Minor: 6. The most serious include Fentanyl, Levetiracetam, Amisulpride.
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