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藥物交互作用

Asenapine + Pyrilamine

嚴重程度: 輕微

Asenapine and Pyrilamine: minor interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Pyrilamine is a sedating antihistamine and, combined with asenapine, may increase drowsiness and reduce psychomotor performance. Anticholinergic effects may also be additive.

用白話說明這項交互作用的意義

Asenapine and Pyrilamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Asenapine belongs to Central Nervous System; Pyrilamine belongs to Respiratory.

證據等級: Low

為什麼會發生

Additive CNS depression through histamine H1 antagonism and other sedative effects.

處置方式

Advise patients about increased drowsiness and avoid driving until response is known. Consider a non-sedating antihistamine if needed.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Asenapine 與 Pyrilamine 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Asenapine with Pyrilamine?

MediHelp rates the interaction as minor. Asenapine and Pyrilamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pyrilamine is a sedating antihistamine and, combined with asenapine, may increase drowsiness and reduce psychomotor performance. Anticholinergic effects may also be additive.

How serious is the interaction between Asenapine and Pyrilamine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about increased drowsiness and avoid driving until response is known. Consider a non-sedating antihistamine if needed.

What other medicines interact with Asenapine?

MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.

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