藥品參考
Rilpivirine
Rilpivirine is a medicine in the class anti virals. It is used for hiv.
- 藥物類別: Anti Virals
- 用途: hiv
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Virals
- ATC 代碼
- J05AG05
- 常見劑型
- 錠劑
- 常見規格
- 2.5 mg, 25 mg
- 已知交互作用
- 111 (禁忌併用: 12 · 嚴重: 15 · 中度: 78 · 輕微: 6)
- 商品名
- 4
- 國家與市場
- 2
用途
作用方式
Rilpivirine is an HIV-1 specific non-nucleoside reverse transcriptase inhibitor (NNRTI) antiviral drug.
成人常用劑量（仿單摘要）
Treatment-naive HIV-1 infection: 25 mg tablet orally once daily with a meal, in combination with other antiretrovirals
懷孕與哺乳
- 懷孕
- Unknown APR data show no difference in overall birth defect risk versus background; rilpivirine exposures are lower during pregnancy, so monitor viral load closely.
- 哺乳
- Unknown Rilpivirine is present in human breast milk; risks include HIV transmission, viral resistance and adverse reactions in infant.
已通報的副作用
- Depressive disorders
- Headache
- Insomnia
- Rash
- Abdominal pain
- Fatigue
禁忌症
- Coadministration with carbamazepine, oxcarbazepine, phenobarbital, phenytoin
- Coadministration with rifampin, rifapentine
- Coadministration with systemic dexamethasone (more than a single dose)
哪些人需要特別留意
- Severe skin and hypersensitivity reactions including DRESS; discontinue immediately if severe rash, fever, blisters, mucosal involvement, angioedema, hepatitis or eosinophilia develop.
- Hepatotoxicity: monitor liver tests, especially with hepatitis B or C co-infection or marked transaminase elevations.
- Depressive disorders including suicidal ideation and suicide attempt; seek immediate medical evaluation for severe symptoms.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (111)
- Carbamazepine + Rilpivirine Contraindicated
- Dexamethasone + Rilpivirine Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Efavirenz + Rilpivirine Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Esomeprazole + Rilpivirine Contraindicated
- Lansoprazole + Rilpivirine Contraindicated
- Omeprazole + Rilpivirine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Pantoprazole + Rilpivirine Contraindicated
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Rilpivirine 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同類別的其他藥品
常見問題
What is Rilpivirine used for?
Rilpivirine is a medicine in the class anti virals. It is used for HIV.
What side effects have been reported with Rilpivirine?
Depressive disorders, Headache, Insomnia, Rash, Abdominal pain, Fatigue.
Can Rilpivirine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. APR data show no difference in overall birth defect risk versus background; rilpivirine exposures are lower during pregnancy, so monitor viral load closely. Breastfeeding: Unknown. Rilpivirine is present in human breast milk; risks include HIV transmission, viral resistance and adverse reactions in infant.
What does Rilpivirine interact with?
MediHelp lists 111 known interactions for Rilpivirine. Contraindicated: 12 · Major: 15 · Moderate: 78 · Minor: 6. The most serious include Carbamazepine, Dexamethasone, Dexlansoprazole.
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